We operate at the intersection of engineering and regenerative medicine with the goal of understanding neurovascular diseases (e.g. disorders that afflict the central nervous system and its surrounding blood vessels) and designing rational therapeutic strategies to combat their progression. Our lab utilizes a diverse spectrum of experimental techniques, including human induced pluripotent stem cell (iPSC) differentiation, genetic engineering, microscale fabrication, and molecular selection/directed evolution. Our platform technologies are intended to facilitate the development of representative tissue models, the design and selection of novel targeting agents and signaling pathway modulators, and the construction of advanced high throughput systems for drug screening and biological discovery.

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